gemcitabine

Adult Dosing .

Dosage forms:  INJ

Special Note

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments

ovarian CA, advanced

[1000 mg/m^2/dose IV x1 on days 1, 8 of 21-day cycle]

Info: for platinum-refractory dz; use w/ carboplatin

breast CA, metastatic

[1250 mg/m^2/dose IV x1 on days 1, 8 of 21-day cycle]

Info: for anthracycline-refractory dz; use w/ paclitaxel

non-small cell lung CA, locally advanced or metastatic

[1000 mg/m^2/dose IV x1 on days 1, 8, 15 of 28-day cycle]

Alt: 1250 mg/m^2/dose IV x1 on days 1, 8 of 21-day cycle; Info: use w/ cisplatin

pancreatic CA, locally advanced or metastatic

[1000 mg/m^2/dose IV x1 on days 1, 8, 15 of 28-day cycle, starting cycle 2]

Start: 1000 mg/m^2/dose IV x1 on days 1, 8, 15, 22, 29, 36, 43 of 56-day cycle for cycle 1

renal dosing

[see below]

renal impairment: not defined, caution advised

HD/PD: not defined, caution advised

hepatic dosing

[see below]

hepatic impairment: not defined, caution advised

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.