diazoxide

Adult Dosing .

Dosage forms:  SUSP: 50 mg per mL

hypoglycemia, hyperinsulinism-associated

[3-8 mg/kg/day PO divided q8-12h]

Start: 3 mg/kg/day PO divided q8-12h; Max: 8 mg/kg/day; Info: refractory cases may require higher dose; D/C if no response in 2-3wk

renal dosing

[see below]

renal impairment: consider decr. dose

HD/PD: not defined, caution advised

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  SUSP: 50 mg per mL

hypoglycemia, hyperinsulinism-associated

[neonates/infants]

Dose: 8-15 mg/kg/day PO divided q8-12h; Start: 8 mg/kg/day PO divided q8-12h; Max: 15 mg/kg/day; Info: D/C if no response in 2-3wk

[children/adolescents]

Dose: 3-8 mg/kg/day PO divided q8-12h; Start: 3 mg/kg/day PO divided q8-12h; Max: 8 mg/kg/day; Info: refractory cases may require higher dose; D/C if no response in 2-3wk

renal dosing

[see below]

renal impairment: consider decr. dose

HD/PD: not defined, caution advised

hepatic dosing

[not defined]