cyclobenzaprine

Adult Dosing .

Dosage forms:  TAB: 5 mg, 7.5 mg, 10 mg; ER CAP: 15mg, 30 mg

muscle spasm

[immediate-release form]

Dose: 5 mg PO tid for up to 2-3wk; Info: may incr. dose to 10 mg PO tid; start 5 mg PO qd, titrate slowly in elderly patients

[extended-release form]

Dose: 15 mg ER PO qd for up to 2-3wk; Info: may incr. dose to 30 mg ER PO qd; may open cap, but do not crush/chew contents

fibromyalgia (off-label)

[10-40 mg/day PO divided qd-tid]

Start: 10 mg PO qhs, may incr. dose as tolerated; Info: divide doses >30 mg/day; start 5 mg PO qd, titrate slowly in elderly patients

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[immediate-release form]

Child-Pugh Class A: start 5 mg qd, titrate slowly; Child-Pugh Class B or C: avoid use

[extended-release form]

hepatic impairment: avoid use

Peds Dosing .

Dosage forms:  TAB: 5 mg, 7.5 mg, 10 mg

muscle spasm

[15 yo and older]

Dose: 5 mg PO tid for up to 2-3wk; Info: may incr. dose to 10 mg PO tid

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[see below]

Child-Pugh Class A: start 5 mg qd, titrate slowly; Child-Pugh Class B or C: avoid use