estradiol vaginal

Adult Dosing .

Dosage forms:  TAB: 10 mcg; CREAM: 0.01%

vulvovaginal atrophy, menopausal

[tablet form]

Dose: 10 mcg PV 2x/wk; Start: 10 mcg PV qd x2wk

[cream form]

Dose: 1 g PV 1-3x/wk; Start: 2-4 g PV qd x2wk, then taper dose gradually over 1-2wk to maintenance dose; Info: 1 g cream = 0.1 mg estradiol

renal dosing

[see below]

renal disease: not defined, caution advised

HD/PD: not defined, caution advised

hepatic dosing

[see below]

hepatic impairment: contraindicated

Peds Dosing .

Dosage forms:  CREAM: 0.01%

fusion of labia (off-label)

[1 mo and older]

Dose: apply bid for up to 6wk

renal dosing

[see below]

renal disease: not defined, caution advised

HD/PD: not defined, caution advised

hepatic dosing

[not defined]

hepatic impairment: consider adult hepatic dosing for guidance