Premarin Vaginal

Adult Dosing .

Dosage forms:  CREAM: 0.625 mg per g

vulvovaginal atrophy

[0.5-2 g PV 1-3x/wk]

Start: 0.5-2 g PV qd x2wk, then taper dose gradually to maintenance dose; Alt: 0.5-2 g PV qd x3wk, off x1wk, repeat

dyspareunia, moderate-severe menopausal

[0.5 g PV 2x/wk]

Alt: 0.5 g PV qd x3wk, off x1wk, repeat

renal dosing

[see below]

renal disease: not defined, caution advised

HD/PD: not defined, caution advised

hepatic dosing

[see below]

hepatic impairment: contraindicated

Peds Dosing .

Dosage forms:  CREAM: 0.625 mg per g

fusion of labia (off-label)

[1 mo and older]

Dose: apply bid for up to 6wk

renal dosing

[see below]

renal disease: not defined, caution advised

HD/PD: not defined, caution advised

hepatic dosing

[not defined]

hepatic impairment: consider adult hepatic dosing for guidance