Depo-Testosterone

Adult Dosing .

Dosage forms:  INJ: 100 mg per mL, 200 mg per mL

primary hypogonadism, male

[50-400 mg IM q2-4wk]

hypogonadotropic hypogonadism, male

[50-400 mg IM q2-4wk]

transgender hormone therapy, masculinizing (off-label)

[50-100 mg SC/IM qwk]

Alt: 100-200 mg IM q2wk; Info: adjust dose based on pt tx goals, clinical response, and testosterone levels; refer to WPATH or Endocrine Society guidelines

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  INJ: 100 mg per mL, 200 mg per mL

primary hypogonadism, male

[puberty induction, 12 yo and older]

Dose: 150-250 mg IM q2-4wk; Start: 25-100 mg IM q4wk x6mo, then incr. by 50 mg/dose q6-12mo; Info: individualize dose based on pt age, skeletal age, and tx response

[maintenance tx, 12 yo and older]

Dose: 50-400 mg IM q2-4wk; Info: adjust dose based on testosterone levels; use lowest effective dose

hypogonadotropic hypogonadism, male

[puberty induction, 12 yo and older]

Dose: 150-250 mg IM q2-4wk; Start: 25-100 mg IM q4wk x6mo, then incr. by 50 mg/dose q6-12mo; Info: individualize dose based on pt age, skeletal age, and tx response

[maintenance tx, 12 yo and older]

Dose: 50-400 mg IM q2-4wk; Info: adjust dose based on testosterone levels; use lowest effective dose

constitutional delay of growth and puberty, male (off-label)

[14 yo and older]

Dose: 25-50 mg IM q4wk x3-6mo; Max: 100 mg/dose; Info: may incr. dose by 25-50 mg after 6mo if spontaneous puberty progression not achieved; reassess tx need q3-6mo

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]