Select a medication above to begin.
Serevent Diskus
salmeterol inhaled
Black Box Warnings .
Asthma-Related Death
long-acting beta-2 adrenergic agonists (LABA) used as monotherapy (w/o inhaled corticosteroids) incr. risk of asthma-related death; data from large placebo-controlled US study showed incr. in asthma-related deaths in pts receiving salmeterol plus usual asthma tx, results considered LABA class effect; use of background inhaled corticosteroid was not required in study; fixed-dose LABA w/ inhaled corticosteroid did not significantly incr. risk of asthma-related events (hospitalization, intubation, death) compared to inhaled corticosteroid alone based on data from large clinical trials; use of LABA monotherapy w/o inhaled corticosteroid is contraindicated in asthma pts; only use LABA as additional therapy in pt currently taking, but inadequately controlled on inhaled corticosteroid; do not use LABA if asthma adequately controlled on low-or medium-dose inhaled corticosteroids
Pediatric and Adolescent Use
long-acting beta-2 adrenergic agonists (LABA) as monotherapy (w/o inhaled corticosteroids) may incr. risk of asthma-related hospitalization in pediatric and adolescent pts; to incr. compliance, consider fixed-dose combination product for asthma pts that require LABA in addition to inhaled corticosteroid; if use of inhaled corticosteroid and LABA is clinically indicated, ensure adherence w/ both treatment components; if adherence cannot be assured, a fixed-dose combination product containing both inhaled corticosteroid and LABA is recommended
Adult Dosing .
Dosage forms: DPI: 50 mcg per actuation
asthma, maintenance tx
- [1 puff inhaled q12h]
- Info: for use only in combo w/ inhaled corticosteroid; use shortest effective tx duration
bronchospasm, exercise-induced
- [1 puff inhaled x1]
- Start: 30-60min before exercise; Max: 1 puff inhaled q12h
COPD, maintenance tx
- [1 puff inhaled q12h]
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [see below]
- hepatic impairment: not defined, caution advised
Peds Dosing .
- Dosage forms: DPI: 50 mcg per actuation
asthma, maintenance tx
- [4 yo and older]
- Dose: 1 puff inhaled q12h; Info: for use only in combo w/ inhaled corticosteroid; fixed-dose combination product preferred to incr. compliance; use shortest effective tx duration
bronchospasm, exercise-induced
- [4 yo and older]
- Dose: 1 puff inhaled x1; Start: 30-60min before exercise; Max: 1 puff inhaled q12h
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [see below]
- hepatic impairment: not defined, caution advised