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Zynteglo
betibeglogene autotemcel
Adult Dosing .
Dosage forms: INJ
Restricted Distribution in US
- [1-833-666-2583 or www.zynteglo.com for more info]
Special Note
- [uses, dosing may vary]
- Info: refer to institution protocols and pkg insert prior to prescribing for uses, prophylactic regimens, and dosing
beta-thalassemia, transfusion-dependent
- [5 x10^6 CD34+ cells/kg/dose IV x1]
- Start: at least 48h after myeloablative conditioning w/ busulfan; Info: maintain Hgb >11 for at least 30 days before mobilization and x30 days before myeloablative conditioning; do not start myeloablative conditioning until confirming betibeglogene autotemcel infusion bag(s) at tx facility and back-up collection of CD34+ cells available
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: INJ
Restricted Distribution in US
- [1-833-666-2583 or www.zynteglo.com for more info]
Special Note
- [uses, dosing may vary]
- Info: refer to institution protocols and pkg insert prior to prescribing for uses, prophylactic regimens, and dosing
beta-thalassemia, transfusion-dependent
- [4 yo and older]
- Dose: 5 x10^6 CD34+ cells/kg/dose IV x1; Start: at least 48h after myeloablative conditioning w/ busulfan; Info: maintain Hgb >11 for at least 30 days before mobilization and x30 days before myeloablative conditioning; do not start myeloablative conditioning until confirming betibeglogene autotemcel infusion bag(s) at tx facility and back-up collection of CD34+ cells available
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]