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oxaliplatin
generic
Black Box Warnings .
Hypersensitivity and Anaphylaxis
serious and fatal rxns can occur w/in minutes of admin. and during any cycle; contraindicated in pts w/ hypersensitivity rxns to oxaliplatin and platinum-based drugs; if hypersensitivity rxns occur, immediately and permanently D/C tx; admin. appropriate tx for management of hypersensitivity rxns
Adult Dosing .
Dosage forms: INJ
Special Note
- [uses, dosing may vary]
- Info: refer to institution protocols and pkg insert prior to prescribing for uses, premeds, and dosing incl. toxicity-related dose adjustments
stage III colon CA, adjuvant tx
- [85 mg/m^2/dose IV x1 on day 1 of 14-day cycle for up to 12 cycles]
- Info: for pts who have undergone complete resection; part of multi-drug chemo regimen
colorectal CA, advanced
- [85 mg/m^2/dose IV x1 on day 1 of 14-day cycle]
- Info: part of multi-drug chemo regimen
renal dosing
- [adjust dose amount]
- CrCl <30: 65 mg/m^2/dose x1 on day 1 of 14-day cycle
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.