albuterol inhaled

Adult Dosing .

Dosage forms:  MDI: 90 mcg per actuation; NEB (0.083%): 2.5 mg per 3 mL; NEB (0.5%): 5 mg per mL

Special Note

[MDI strength clarification]

Info: 1 actuation = 108 mcg albuterol sulfate equivalent to 90 mcg albuterol base

[NEB strength clarification]

Info: all strengths expressed as albuterol base

bronchospasm

[MDI form]

Dose: 2 puffs inhaled q4-6h prn; Alt: 1 puff inhaled q4h prn

[NEB form]

Dose: 2.5 mg NEB tid-qid prn; Max: 10 mg/day

bronchospasm, acute

[NEB form, mild-moderate exacerbation]

Dose: 2.5-5 mg NEB q20min x3, then 2.5-10 mg NEB q1-4h prn; Alt: 10-15 mg/h continuous NEB

[NEB form, severe exacerbation]

Dose: 5 mg NEB q20min x3, then 10 mg NEB q1-4h prn; Alt: 15 mg/h continuous NEB

[MDI form, mild-moderate exacerbation (off-label)]

Dose: 4-8 puffs inhaled q20min up to 4h, then 4-8 puffs inhaled q1-4h prn

[MDI form, severe exacerbation (off-label)]

Dose: 4-12 puffs inhaled q20min up to 4h, then 4-12 puffs inhaled q1-4h prn

bronchospasm, exercise-induced

[MDI form]

Dose: 2 puffs inhaled x1; Start: 5-30min before exercise

hyperkalemia, adjunct tx (off-label)

[NEB form]

Dose: 10-20 mg NEB x1

renal dosing

[see below]

renal impairment: not defined; Info: caution advised if high-dose use

HD/PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  MDI: 90 mcg per actuation; NEB (0.021%): 0.63 mg per 3 mL; NEB (0.042%): 1.25 mg per 3 mL; NEB (0.083%): 2.5 mg per 3 mL; NEB (0.5%): 5 mg per mL

Special Note

[MDI strength clarification]

Info: 1 actuation = 108 mcg albuterol sulfate equivalent to 90 mcg albuterol base

[NEB strength clarification]

Info: all strengths expressed as albuterol base

bronchospasm

[MDI form, <4 yo (off-label)]

Dose: 2 puffs inhaled q4-6h prn; Alt: 1 puff inhaled q4h prn

[MDI form, 4 yo and older]

Dose: 2 puffs inhaled q4-6h prn; Alt: 1 puff inhaled q4h prn

[NEB form, <2 yo (off-label)]

Dose: 0.63-2.5 mg NEB q4-6h prn

[NEB form, 2-4 yo]

Dose: 0.63-2.5 mg NEB q4-6h prn

[NEB form, 5 yo and older]

Dose: 1.25-5 mg NEB q4-8h prn

bronchospasm, acute

[NEB form, <2 yo, mild-moderate exacerbation (off-label)]

Dose: 0.15 mg/kg/dose (min 2.5 mg) NEB q20min x3, then 2.5-10 mg NEB q1-4h prn; Alt: 0.15 mg/kg/dose (min 2.5 mg) NEB q20min x3, then 0.5 mg/kg/h continuous NEB

[NEB form, <2 yo, severe exacerbation (off-label)]

Dose: 0.15 mg/kg/dose (min 2.5 mg) NEB q20min x3, then 2.5-10 mg NEB q1-4h prn; Alt: 0.15 mg/kg/dose (min 2.5 mg) NEB q20min x3, then 0.5 mg/kg/h continuous NEB

[NEB form, 2-11 yo, mild-moderate exacerbation]

Dose: 0.15 mg/kg/dose (min 2.5 mg) NEB q20min x3, then 2.5-10 mg NEB q1-4h prn; Alt: 0.15 mg/kg/dose (min 2.5 mg) NEB q20min x3, then 0.5 mg/kg/h continuous NEB

[NEB form, 2-11 yo, severe exacerbation]

Dose: 0.15 mg/kg/dose (min 2.5 mg) NEB q20min x3, then 2.5-10 mg NEB q1-4h prn; Alt: 0.15 mg/kg/dose (min 2.5 mg) NEB q20min x3, then 0.5 mg/kg/h continuous NEB

[NEB form, 12 yo and older, mild-moderate exacerbation]

Dose: 2.5-5 mg NEB q20min x3, then 2.5-10 mg NEB q1-4h prn; Alt: 10-15 mg/h continuous NEB

[NEB form, 12 yo and older, severe exacerbation]

Dose: 5 mg NEB q20min x3, then 10 mg NEB q1-4h prn; Alt: 15 mg/h continuous NEB

[MDI form, <12 yo, mild-moderate exacerbation (off-label)]

Dose: 4-8 puffs inhaled q20min x3, then 4-8 puffs inhaled q1-4h prn

[MDI form, 1-11 yo, severe exacerbation (off-label)]

Dose: 4-8 puffs inhaled q20min x3, then 4-8 puffs inhaled q1-4h prn

[MDI form, 12 yo and older, mild-moderate exacerbation (off-label)]

Dose: 4-8 puffs inhaled q20min x3, then 4-8 puffs inhaled q1-4h prn

[MDI form, 12 yo and older, severe exacerbation (off-label)]

Dose: 4-12 puffs inhaled q20min x3, then 4-12 puffs inhaled q1-4h prn

bronchospasm, exercise-induced

[MDI form, <4 yo (off-label)]

Dose: 1-2 puffs inhaled x1; Start: 5-30min before exercise

[MDI form, 4 yo and older]

Dose: 2 puffs inhaled x1; Start: 5-30min before exercise

hyperkalemia, adjunct tx (off-label)

[NEB form, infants/children, <25 kg]

Dose: 2.5 mg NEB q20min x1-2 doses

[NEB form, children, 25-50 kg]

Dose: 5 mg NEB q20min x1-2 doses

[NEB form, children, >50 kg]

Dose: 10 mg NEB q20min x1-2 doses

renal dosing

[see below]

renal impairment: not defined; Info: caution advised if high-dose use

HD/PD: not defined

hepatic dosing

[not defined]