Prilosec OTC

Uses .

[ omeprazole ]

proton pump inhibitor for relieving recurrent heartburn, H. pylori infection

Dosing .

heartburn

[ adults ]

Dose: 1 tab PO qd x14 days; Max: 1 tab/24h; Info: give before meals; do not cut/crush/chew tab

H. pylori infection (off-label)

[ children, 15-24 kg ]

Dose: 20 mg PO bid x10-14 days; Info: part of multi-drug regimen; give >15min before meals; do not cut/crush/chew tab; search 'H. pylori Tx' for epocrates H. pylori Tx Regimens decision tool

[ children, 25-34 kg ]

Dose: 30 mg PO bid x10-14 days; Info: part of multi-drug regimen; give >15min before meals; use oral granules, not avail. for this brand; see other omeprazole products; do not cut/crush/chew tab; search 'H. pylori Tx' for epocrates H. pylori Tx Regimens decision tool

[ children, >35 kg ]

Dose: 40 mg PO bid x10-14 days; Info: part of multi-drug regimen; give >15min before meals; do not cut/crush/chew tab; search 'H. pylori Tx' for epocrates H. pylori Regimens decision tool

[ adults ]

Dose: 20-40 mg PO bid x14 days; Info: part of multi-drug regimen, dosing may vary; give before meals; do not cut/crush/chew tab; search 'H. pylori Tx' for epocrates H. Pylori Tx Regimens decision tool

eosinophilic esophagitis (off-label)

[ children/adolescents ]

Dose: 2 mg/kg/day PO divided qd-bid x8-12wk, then taper to lowest effective dose; Max: 40 mg/day; Info: consider decr. maint. dose in Asian patients (incr. risk of CYP2C19 poor metabolizer); give before meals; do not cut/crush/chew tab

[ adults ]

Dose: 40 mg/day PO divided qd-bid x8-12wk, then taper to lowest effective dose; Info: consider decr. maint. dose in Asian patients (incr. risk of CYP2C19 poor metabolizer); give before meals; do not cut/crush/chew tab

renal dosing

[ no adjustment ]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[ not defined ]