Boostrix

Adult Dosing .

Dosage forms:  INJ

diphtheria, tetanus and pertussis prevention

[primary (off-label)]

Dose: 0.5 mL IM x2 doses at least 4wk apart, then 0.5 mL IM x1 dose 6-12mo later; Info: for pts who did not previously complete DT or DTaP vaccine series; may substitute w/ Td vaccine if Tdap vaccine used for at least 1 dose; search 'immunization' for epocrates Adult Immunization decision tool incl. links to CDC/ACIP schedules

[booster, non-pregnant pts]

Dose: 0.5 mL IM q10y; Info: search 'immunization' for epocrates Adult Immunization decision tool incl. links to CDC/ACIP schedules

[booster, pregnant pts]

Dose: 0.5 mL IM x1 at 27-36 wk gestation; Info: search 'immunization' for epocrates Adult Immunization decision tool incl. links to CDC/ACIP schedules

tetanus-prone wound management

[0.5 mL IM x1 dose]

Info: for pts who received 3 or more doses of tetanus-toxoid-containing vaccine if >5y since last dose; search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[no adjustment]

Peds Dosing .

Dosage forms:  INJ

diphtheria, tetanus and pertussis prevention

[primary, 7 yo and older (off-label)]

Dose: 0.5 mL IM x2 doses at least 4wk apart, then 0.5 mL IM x1 dose 6-12mo later; Info: for pts who did not previously complete DT or DTaP vaccine series; may substitute w/ Td vaccine if Tdap vaccine used for at least 1 dose; search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

[booster, 11 yo and older, non-pregnant pts]

Dose: 0.5 mL IM x1 at 11-12 yo, then q10y; Info: search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

[booster, 11 yo and older, pregnant pts]

Dose: 0.5 mL IM x1 at 27-36 wk gestation; Info: search 'immunization' for epocrates Adult Immunization decision tool incl. links to CDC/ACIP schedules

tetanus-prone wound management

[7 yo and older]

Dose: 0.5 mL IM x1 dose; Info: for pts who received 3 or more doses of tetanus-toxoid-containing vaccine if >5y since last dose; search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[no adjustment]