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terbutaline
generic
Black Box Warnings .
Tocolysis Use
oral terbutaline not approved for and should not be used for acute or maintenance tocolysis; injectable terbutaline not approved for and should not be used for prolonged tocolysis >48-72h; do not use for maintenance tocolysis in outpatient or home setting; serious adverse rxns incl. incr. heart rate, transient hyperglycemia, hypokalemia, cardiac arrhythmias, pulmonary edema, MI, and death reported after use in pregnant pts; incr. fetal heart rate and neonatal hypoglycemia may also occur
Adult Dosing .
Dosage forms: TAB: 2.5 mg, 5 mg; INJ: various
bronchospasm, acute
- [0.25 mg SC x1, then may repeat dose x1 after 15-30min]
- Max: 0.5 mg/4h; Alt: 0.25 mg SC q20min x3
bronchospasm
- [2.5-5 mg PO tid]
- Max: 15 mg/day; Info: not recommended per GINA guidelines; separate doses by approx. 6h
tocolysis, acute (off-label)
- [0.25 mg SC q20min-3h]
- Max: 48-72h; Info: hold for HR >120
renal dosing
- [see below]
- CrCl 10-50: decr. usual dose by 50%; CrCl <10: not defined, caution advised
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: TAB: 2.5 mg, 5 mg; INJ: various
bronchospasm, acute
- [<12 yo (off-label)]
- Dose: 0.01 mg/kg/dose SC q20min x3, then 0.01 mg/kg/dose SC q2-6h prn
- [12 yo and older]
- Dose: 0.25 mg SC x1, then may repeat dose x1 after 15-30min; Max: 0.5 mg/4h; Alt: 0.25 mg SC q20min x3
bronchospasm
- [12-15 yo]
- Dose: 2.5 mg PO tid; Max: 7.5 mg/day; Info: not recommended per GINA guidelines; separate doses by approx. 6h
- [16 yo and older]
- Dose: 2.5-5 mg PO tid; Max: 15 mg/day; Info: not recommended per GINA guidelines; separate doses by approx. 6h
renal dosing
- [adjust dose amount]
- CrCl <50: decr. usual dose, amount not defined
- HD/PD: not defined
hepatic dosing
- [not defined]