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terbutaline
generic
Black Box Warnings .
Tocolysis Use
oral terbutaline not approved for and should not be used for acute or maintenance tocolysis; injectable terbutaline not approved for and should not be used for prolonged tocolysis >48-72h; do not use for maintenance tocolysis in outpatient or home setting; serious adverse rxns incl. incr. heart rate, transient hyperglycemia, hypokalemia, cardiac arrhythmias, pulmonary edema, MI, and death reported after use in pregnant women; incr. fetal heart rate and neonatal hypoglycemia may also occur
Adult Dosing .
Dosage forms: TAB: 2.5 mg, 5 mg; INJ: various
bronchospasm
- [2.5-5 mg PO tid]
- Max: 15 mg/day PO; 0.5 mg/4h SC; Alt: 0.25 mg SC q15-30min x2; Info: admin. PO dose q6h while awake
tocolysis (off-label)
- [0.25 mg SC q1-6h]
- Start: 0.25 mg SC q20-30min; Max: 1 mg/4h SC x48-72h; 0.025 mg/min IV x48-72h; Alt: 0.0025-0.01 mg/min IV, incr. 0.005 mg/min q10min until contractions stop or max dose
renal dosing
- [see below]
- CrCl 10-50: decr. usual dose by 50%; CrCl <10: not defined, caution advised
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: TAB: 2.5 mg, 5 mg; INJ: various
bronchospasm
- [6-11 yo]
- Dose: 0.05 mg/kg/dose PO tid, give q6h while awake; Max: 0.15 mg/kg/dose or 5 mg/day PO; 0.4 mg/dose SC; Alt: 0.005-0.01 mg/kg/dose SC q15-30min x2
- [12-15 yo]
- Dose: 2.5 mg PO tid, admin. q6h while awake; Max: 7.5 mg/day PO; 0.5 mg/4h SC; Alt: 0.25 mg SC q15-30min x2
- [>15 yo]
- Dose: 2.5-5 mg PO tid, admin. q6h while awake; Max: 15 mg/day PO; 0.5 mg/4h SC; Alt: 0.25 mg SC q15-30min x2
renal dosing
- [adjust dose amount]
- CrCl <50: decr. usual dose, amount not defined
- HD/PD: not defined
hepatic dosing
- [not defined]