Drisdol

Adult Dosing .

Dosage forms:  CAP: 50,000 units; SOL: 8000 units per mL

Special Note

[strength clarification]

Info: doses expressed in units; 40 units = 1 mcg

hypoparathyroidism adjunct

[50,000-200,000 units PO qd]

Start: 50,000 units PO qd

vitamin D deficiency

[1500-2000 units PO qd]

Start: 50,000 units PO qwk or 6000 units PO qd x8wk; Info: incr. dose 2-fold to 3-fold if obese, malabsorption syndrome, drug-induced vitamin D deficiency

osteomalacia (off-label)

[drug-induced]

Dose: 4000 units PO qd

[malabsorption-related]

Dose: 10,000-50,000 units PO qd

[nutritional deficiency-related]

Dose: 50,000 units PO 1-2x/wk x6-12mo

[renal tubular acidosis-related]

Dose: 5000-10,000 units PO qd

dietary supplementation

[individualize dose]

Info: see Dietary Reference Intakes: Vitamin D (calciferols) table

renal dosing

[see below]

renal impairment: not defined; Info: caution advised if advanced chronic kidney disease

HD/PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  CAP: 50,000 units; SOL: 8000 units per mL

Special Note

[strength clarification]

Info: doses expressed in units; 40 units = 1 mcg

hypoparathyroidism adjunct

[50,000-200,000 units PO qd]

Start: 50,000 units PO qd

vitamin D deficiency

[<1 yo]

Dose: 400-1000 units PO qd; Start: 2000 units PO qd or 50,000 units PO qwk x6wk

[1 yo and older]

Dose: 600-1000 units PO qd; Start: 2000 units PO qd or 50,000 units PO qwk x6wk

rickets, vitamin D deficient (off-label)

[<1 mo]

Dose: 1000 units PO qd; Info: give w/ Ca; may decr. dose to 400 units/day after evidence of healing; 400 units = 2 gtt 8000 units per mL form

[1-11 mo]

Dose: 1000-5000 units PO qd; Info: give w/ Ca; may decr. dose to 400 units/day after evidence of healing; 400 units = 2 gtt 8000 units per mL form

[1 yo and older]

Dose: 5000 units PO qd; Alt: 150,000-300,000 units PO x1, may repeat after 3mo; Info: give w/ Ca; may decr. dose to 400 units/day after evidence of healing; 400 units = 2 gtt 8000 units per mL form

dietary supplementation

[individualize dose]

Info: see Dietary Reference Intakes: Vitamin D (calciferols) table

renal dosing

[not defined]

renal impairment: consider adult renal dosing for guidance

HD/PD: not defined

hepatic dosing

[not defined]