Toviaz

Adult Dosing .

Dosage forms:  ER TAB: 4 mg, 8 mg

overactive bladder

[4-8 mg PO qd]

Start: 4 mg PO qd, may incr. to 8 mg PO qd; Max: 8 mg/day; Info: do not cut/crush/chew tab

renal dosing

[adjust dose amount]

CrCl <30: max 4 mg/day

HD/PD: not defined

hepatic dosing

[see below]

Child-Pugh Class C: avoid use

Peds Dosing .

Dosage forms:  ER TAB: 4 mg, 8 mg

detrusor overactivity, neurogenic

[6 yo and older, 26-35 kg]

Dose: 4-8 mg PO qd; Start: 4 mg PO qd, may incr. to 8 mg PO qd; Info: do not cut/crush/chew tab

[6 yo and older, >35 kg]

Dose: 8 mg PO qd; Start: 4 mg PO qd, then incr. to 8 mg PO qd after 1wk; Info: do not cut/crush/chew tab

renal dosing

[6 yo and older, 26-35 kg]

CrCl 30-89: max 4 mg/day; CrCl <30: avoid use

HD/PD: avoid use

[6 yo and older, >35 kg]

CrCl 15-30: max 4 mg/day; CrCL <15: avoid use

HD/PD: avoid use

hepatic dosing

[see below]

Child-Pugh Class C: avoid use