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Tylenol PM
acetaminophen/ diphenhydramine
Uses .
- [ acetaminophen ]
- analgesic for reducing pain; antipyretic for reducing fever
- [ diphenhydramine ]
- antihistamine for promoting sleep
Dosing .
12 yo and older
- [ oral tablet ]
- Dose: 2 tabs PO qhs prn; Max: 2 tabs/24h; 4 g/day acetaminophen from all sources
- [ oral solution ]
- Dose: 30 mL PO qhs prn; Max: 30 mL/24h; 4 g/day acetaminophen from all sources
renal considerations
- [ acetaminophen; diphenhydramine ]
- CrCl <50: consider alternatives, dose adjustment not possible w/ fixed-dose combo
- HD/PD: consider alternatives, dose adjustment not possible w/ fixed-dose combo
hepatic considerations
- [ acetaminophen; diphenhydramine ]
- hepatic impairment: consider alternatives, dose adjustment not possible w/ fixed-dose combo