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Cambia
diclofenac potassium
Black Box Warnings .
Cardiovascular Thrombotic Event
NSAIDs incr. risk of serious and potentially fatal cardiovascular thrombotic events, including MI and stroke; risk may occur early in tx and may incr. with duration of use; contraindicated in CABG periop setting
GI Bleeding, Ulceration, and Perforation
NSAIDs incr. risk of serious and potentially fatal GI adverse events including bleeding, ulcer, and stomach or intestine perforation; GI events may occur at any time during use and without warning symptoms; elderly patients and patients with history of PUD or GI bleeding at greater risk for serious GI events
Adult Dosing .
Dosage forms: POWDER: 50 mg per packet
Special Note
- [equivalency or interchangeability info]
- Info: diclofenac potassium products may not be interchangeable with other diclofenac potassium, diclofenac sodium, or diclofenac products; reassess dose if switching between products
migraine, acute
- [50 mg PO x1]
- Info: give on empty stomach, but may give with food if GI upset occurs
renal dosing
- [see below]
- CrCl <30: avoid use
- HD/PD: avoid use
hepatic dosing
- [see below]
- hepatic impairment: not defined, caution advised
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.