Select a medication above to begin.
Vpriv
velaglucerase alfa
Black Box Warnings .
Hypersensitivity Reaction
life-threatening reactions including anaphylaxis have occurred; anaphylaxis has occurred during early tx and after extended tx duration; administer where appropriate medical support including cardiopulmonary resuscitation equip. available; D/C immediately and start appropriate tx if severe reaction occurs; counsel patients on signs/symptoms and to seek immediate medical attention if they occur at any time
Adult Dosing .
Dosage forms: INJ
Gaucher disease, type 1
- [individualize dose IV q2wk]
- Start: 60 units/kg/dose IV q2wk; Info: if switching from another enzyme replacement tx, start with previous enzyme replacement dose 2wk after last administration; consider premed with antihistamine, corticosteroid if hypersensitivity reaction
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: INJ
Gaucher disease, type 1
- [4 yo and older]
- Dose: individualize dose IV q2wk; Start: 60 units/kg/dose IV q2wk; Info: if switching from another enzyme replacement tx, start with previous enzyme replacement dose 2wk after last administration; consider premed with antihistamine, corticosteroid if hypersensitivity reaction
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]