Select a medication above to begin.
Cerezyme
imiglucerase
Black Box Warnings .
Hypersensitivity Reaction
life-threatening reactions including anaphylaxis have occurred; anaphylaxis has occurred during early tx and after extended tx duration; administer where appropriate medical support including cardiopulmonary resuscitation equip. available; D/C immediately and start appropriate tx if severe reaction occurs; counsel patients on signs/symptoms and to seek immediate medical attention if they occur at any time
Adult Dosing .
Dosage forms: INJ
Gaucher disease, type 1 or type 3
- [2.5 units/kg/dose IV 3x/wk up to 60 units/kg/dose IV q2wk]
- Info: for non-CNS manifestations; individualize dose, frequency based on disease severity, clinical response; if switching from another enzyme replacement tx, start with previous enzyme replacement dose 2wk after last administration; premed with antihistamine and/or corticosteroid if hypersensitivity reaction
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: INJ
Gaucher disease, type 1 or type 3
- [2.5 units/kg/dose IV 3x/wk up to 60 units/kg/dose IV q2wk]
- Info: for non-CNS manifestations; individualize dose, frequency based on disease severity, clinical response; if switching from another enzyme replacement tx, start with previous enzyme replacement dose 2wk after last administration; premed with antihistamine and/or corticosteroid if hypersensitivity reaction
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]