Kuvan

Adult Dosing .

Dosage forms:  TAB: 100 mg; POWDER: 100 mg per packet, 500 mg per packet

PKU

[5-20 mg/kg/dose PO qd]

Start: 10-20 mg/kg/dose PO qd; Info: adjust dose based on phenylalanine levels; give with food; D/C tx if no decr. in phenylalanine levels at 20 mg/kg/day dose x1mo

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  TAB: 100 mg; POWDER: 100 mg per packet, 500 mg per packet

PKU

[1 mo-6 yo]

Dose: 5-20 mg/kg/dose PO qd; Start: 10 mg/kg/dose PO qd; Info: adjust dose based on phenylalanine levels; give with food; D/C tx if no decr. in phenylalanine levels at 20 mg/kg/day dose x1mo

[7 yo and older]

Dose: 5-20 mg/kg/dose PO qd; Start: 10-20 mg/kg/dose PO qd; Info: adjust dose based on phenylalanine levels; give with food; D/C tx if no decr. in phenylalanine levels at 20 mg/kg/day dose x1mo

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]