Select a medication above to begin.
Lumizyme
alglucosidase alfa
Black Box Warnings .
Hypersensitivity Reaction
life-threatening reactions including anaphylaxis have occurred; anaphylaxis has occurred during early tx and after extended tx duration; administer where appropriate medical support including cardiopulmonary resuscitation equip. available; D/C immediately and start appropriate tx if severe reaction occurs; counsel patients on signs/symptoms and to seek immediate medical attention if they occur at any time
Immune-Mediated Reaction
reactions presenting as proteinuria, nephrotic syndrome, and necrotizing skin lesions have occurred; monitor for systemic reactions involving skin and other organs during tx
Cardiorespiratory Failure Risk
perform additional monitoring in infantile-onset Pompe disease patients with compromised cardiac or respiratory function; risk of serious exacerbation of compromised cardiac or respiratory function due to fluid overload
Adult Dosing .
Dosage forms: INJ
Pompe disease
- [20 mg/kg/dose IV q2wk]
- Info: consider premed with antipyretic, antihistamine, corticosteroids
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: INJ
Pompe disease
- [20 mg/kg/dose IV q2wk]
- Info: consider premed with antipyretic, antihistamine, corticosteroids
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]