Select a medication above to begin.
Elaprase
idursulfase
Black Box Warnings .
Anaphylaxis Risk
life-threatening reactions have occurred during and up to 24h after infusion regardless of tx duration; signs/symptoms include respiratory distress, hypoxia, hypotension, urticaria, and/or tongue/throat angioedema; observe patients during and after administration; inform patients of signs/symptoms and to seek immediate medical care if they occur; additional monitoring required for patients with compromised respiratory function or acute respiratory disease due to risk of serious acute respiratory exacerbation from hypersensitivity reactions
Adult Dosing .
Dosage forms: INJ
mucopolysaccharidosis II
- [0.5 mg/kg/dose IV qwk]
- Info: consider premed with antihistamine, corticosteroid
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: INJ
mucopolysaccharidosis II
- [5 yo and older]
- Dose: 0.5 mg/kg/dose IV qwk; Info: consider premed with antihistamine, corticosteroid
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]