Select a medication above to begin.
Aldurazyme
laronidase
Black Box Warnings .
Hypersensitivity Reaction
life-threatening reactions including anaphylaxis have occurred; administer where appropriate medical support including cardiopulmonary resuscitation equip. available; D/C immediately and start appropriate tx if severe reaction occurs; may consider desensitization procedure in patients with severe reaction
Acute Respiratory Complication Risk
patients with compromised respiratory function or acute respiratory disease may be at risk of serious acute exacerbations of their respiratory compromise from infusion reactions; perform additional monitoring in these patients
Adult Dosing .
Dosage forms: INJ
mucopolysaccharidosis I
- [0.58 mg/kg/dose IV qwk]
- Info: for patients with Hurler, Hurler-Scheie, and moderate-severe Scheie forms; consider premed with antihistamine +/- antipyretic
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: INJ
mucopolysaccharidosis I
- [6 mo and older]
- Dose: 0.58 mg/kg/dose IV qwk; Info: for patients with Hurler, Hurler-Scheie, and moderate-severe Scheie forms; consider premed with antihistamine +/- antipyretic
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]