Select a medication above to begin.
Xgeva
denosumab
Adult Dosing .
Dosage forms: INJ: 120 mg per 1.7 mL
bone metastases, solid tumor-associated
- [120 mg SC q4wk]
- Info: for skeletal-related events prevention; avoid invasive dental procedure; calcium and vitamin D supplementation recommended
skeletal-related event prevention, multiple myeloma-associated
- [120 mg SC q4wk]
- Info: avoid invasive dental procedure; calcium and vitamin D supplementation recommended
giant cell tumor of bone, unresectable
- [120 mg SC q4wk]
- Start: 120 mg SC qwk x3wk, then starting wk 5, 120 mg SC q4wk; Info: avoid invasive dental procedure; calcium and vitamin D supplementation recommended
hypercalcemia, malignant
- [120 mg SC q4wk]
- Start: 120 mg SC qwk x3wk, then starting wk 5, 120 mg SC q4wk; Info: avoid invasive dental procedure
renal dosing
- [no adjustment]
- renal impairment: no adjustment
- HD/PD: no adjustment; no supplement
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: INJ: 120 mg per 1.7 mL
giant cell tumor of bone, unresectable
- [adolescents w/ skeletal maturity]
- Dose: 120 mg SC q4wk; Start: 120 mg SC qwk x3wk, then starting wk 5, 120 mg SC q4wk; Info: avoid invasive dental procedure; calcium and vitamin D supplementation recommended
renal dosing
- [no adjustment]
- renal impairment: no adjustment
- HD/PD: no adjustment; no supplement
hepatic dosing
- [not defined]