Select a medication above to begin.
Erivedge
vismodegib
Black Box Warnings .
Embryo-Fetal Death and Severe Birth Defects
embryotoxic, fetotoxic, and teratogenic in animals, incl. severe midline defects, missing digits, and other irreversible malformations; verify pregnancy status w/in 7 days before tx start; advise pts of childbearing potential of need for contraception during and after tx; advise male pts of potential exposure risk via semen and need for condoms during and after tx
Adult Dosing .
Dosage forms: CAP: 150 mg
Restricted Distribution in US
- [1-888-249-4918 or ErivedgeAccessSolutions.com for more info]
Special Note
- [uses, dosing may vary]
- Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments
basal cell CA, locally advanced or metastatic
- [150 mg PO qd]
- Info: do not open cap
renal dosing
- [see below]
- CrCl >30: no adjustment; CrCl <30: not defined
- HD/PD: not defined
hepatic dosing
- [no adjustment]
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.