Voraxaze

Adult Dosing .

Dosage forms:  INJ

methotrexate toxicity

[50 units/kg/dose IV x1]

Info: for pts w/ methotrexate concentration >2 standard deviations above expected mean methotrexate excretion curve

renal dosing

[see below]

renal impairment: no adjustment

HD/PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  INJ

methotrexate toxicity

[50 units/kg/dose IV x1]

Info: for pts w/ methotrexate concentration >2 standard deviations above expected mean methotrexate excretion curve

renal dosing

[see below]

renal impairment: no adjustment

HD/PD: not defined

hepatic dosing

[not defined]