Select a medication above to begin.
Stribild
elvitegravir/ cobicistat/ emtricitabine/ tenofovir disoproxil
Black Box Warnings .
Hepatitis B Exacerbation
severe acute HBV exacerbations in HBV/HIV co-infected patients when D/C emtricitabine or tenofovir; monitor hepatic function closely for at least several months in HBV/HIV co-infected patients who D/C elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil; initiate anti-HBV tx if needed
Adult Dosing .
Dosage forms: TAB: 150 mg/150 mg/200 mg/300 mg
HIV infection
- [1 tab PO qd]
- Info: give with food
HIV post-exposure prophylaxis, occupational (off-label)
- [1 tab PO qd]
- Info: refer to HIV Post-Exposure Prophylaxis, Occupational table; give with food
renal dosing
- [see below]
- CrCl <70: avoid tx initiation; Info: D/C if CrCl <50 during tx; dose adjustment not possible with fixed-dose combo
- HD/PD: not defined
hepatic dosing
- [see below]
- Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined
Peds Dosing .
- Dosage forms: TAB: 150 mg/150 mg/200 mg/300 mg
HIV infection
- [12 yo and older, >35 kg]
- Dose: 1 tab PO qd; Info: for patients with sexual maturity rating 4 or 5; give with food
renal dosing
- [see below]
- CrCl <70: avoid tx initiation; Info: D/C if CrCl <50 during tx; dose adjustment not possible with fixed-dose combo
- HD/PD: not defined
hepatic dosing
- [see below]
- Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined