Xofigo

Adult Dosing .

Dosage forms:  INJ

Restricted Distribution in US

[1-855-696-3446 or www.xofigo-us.com for more info]

Special Note

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for XRT safety procedures, uses, and dosing incl. toxicity-related dose adjustments

prostate CA, metastatic castration-resistant

[55 kBq/kg/dose IV q4wk x6 doses]

Info: for pts w/ symptomatic bone metastases and no known visceral metastatic dz; refer to pkg insert prior to prescribing for dosing and decay correction factor table

renal dosing

[see below]

CrCl >30: no adjustment; CrCl <30: not defined

HD/PD: not defined

hepatic dosing

[see below]

mild impairment: no adjustment; moderate-severe impairment: not defined

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.