Select a medication above to begin.
Vimizim
elosulfase alfa
Black Box Warnings .
Hypersensitivity Reaction
life-threatening reactions including anaphylaxis have occurred; anaphylaxis has occurred during early tx and after extended tx duration; administer where appropriate medical support including cardiopulmonary resuscitation equip. available; D/C immediately and start appropriate tx if severe reaction occurs; counsel patients on signs/symptoms and to seek immediate medical attention if they occur at any time
Acute Respiratory Complication Risk
additional monitoring required for patients with acute respiratory disease due to risk of serious acute respiratory exacerbation from hypersensitivity reactions
Adult Dosing .
Dosage forms: INJ
mucopolysaccharidosis IVA
- [2 mg/kg/dose IV qwk]
- Info: premed with antihistamine +/- antipyretic 30-60min before infusion
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: INJ
mucopolysaccharidosis IVA
- [5 yo and older]
- Dose: 2 mg/kg/dose IV qwk; Info: premed with antihistamine +/- antipyretic 30-60min before infusion
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]