Dalvance

Adult Dosing .

Dosage forms:  INJ

skin/skin structure infections, acute bacterial

[1500 mg IV x1]

Alt: 1000 mg IV x1, then 1wk later, 500 mg IV x1

renal dosing

[one-dose regimen]

CrCl <30: 1125 mg x1

HD: no adjustment; no supplement; PD: not defined

[two-dose regimen]

CrCl <30: 750 mg x1, then 1wk later, 375 mg x1

HD: no adjustment; no supplement; PD: not defined

hepatic dosing

[see below]

Child-Pugh Class A: no adjustment; Child-Pugh Class B or C: not defined, caution advised

Peds Dosing .

Dosage forms:  INJ

skin/skin structure infections, acute bacterial

[<6 yo]

Dose: 22.5 mg/kg/dose IV x1; Max: 1500 mg/dose

[6 yo and older]

Dose: 18 mg/kg/dose IV x1; Max: 1500 mg/dose

renal dosing

[see below]

CrCl >30: no adjustment; CrCl <30: not defined, consider adult renal dosing for guidance

HD: not defined, consider adult renal dosing for guidance; PD: not defined

hepatic dosing

[see below]

Child-Pugh Class A: no adjustment; Child-Pugh Class B or C: not defined, caution advised