Jardiance

Adult Dosing .

Dosage forms:  TAB: 10 mg, 25 mg

diabetes mellitus, type 2

[10-25 mg PO qam]

Start: 10 mg PO qam; Info: hold tx at least 3 days before surgery/procedure if prolonged fasting

cardiovascular event risk reduction - DM type 2 patients with established cardiovascular disease

[10 mg PO qam]

Info: may incr. dose to 25 mg PO qam if additional glycemic control needed; hold tx at least 3 days before surgery/procedure if prolonged fasting

heart failure-associated risk reduction - heart failure patients

[10 mg PO qam]

Info: hold tx at least 3 days before surgery/procedure if prolonged fasting

kidney disease progression and cardiovascular-associated risk reduction - CKD patients with progression risk

[10 mg PO qam]

Info: hold tx at least 3 days before surgery/procedure if prolonged fasting

renal dosing

[diabetes mellitus, type 2]

eGFR <30: avoid use for glycemic control

HD/PD: not defined

[all other indications]

eGFR >20: no adjustment; eGFR <20: not defined; Info: if eGFR <20 during tx, may continue 10 mg/day for cardiovascular or kidney benefit

HD/PD: not defined

hepatic dosing

[no adjustment]

Peds Dosing .

Dosage forms:  TAB: 10 mg, 25 mg

diabetes mellitus, type 2

[10 yo and older]

Dose: 10-25 mg PO qam; Start: 10 mg PO qam; Info: hold tx at least 3 days before surgery/procedure if prolonged fasting

renal dosing

[see below]

renal impairment: not defined, consider adult renal dosing for guidance

HD/PD: not defined

hepatic dosing

[no adjustment]