Cholbam

Adult Dosing .

Dosage forms:  CAP: 50 mg, 250 mg

bile acid synthesis disorder, single enzyme defect-assoc.

[10-15 mg/kg/day PO divided qd-bid]

Info: consider 11-17 mg/kg/day PO divided qd-bid if concomitant familial hypertriglyceridemia; give w/ food

peroxisomal disorder, adjunct tx

[10-15 mg/kg/day PO divided qd-bid]

Info: for pts w/ liver dz manifestations, steatorrhea, or complications from decr. fat soluble vitamin absorption; consider 11-17 mg/kg/day PO divided qd-bid if concomitant familial hypertriglyceridemia; give w/ food

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  CAP: 50 mg, 250 mg

bile acid synthesis disorder, single enzyme defect-assoc.

[3 wk old and older]

Dose: 10-15 mg/kg/day PO divided qd-bid; Info: consider 11-17 mg/kg/day PO divided qd-bid if concomitant familial hypertriglyceridemia; give w/ food

peroxisomal disorder, adjunct tx

[3 wk old and older]

Dose: 10-15 mg/kg/day PO divided qd-bid; Info: for pts w/ liver dz manifestations, steatorrhea, or complications from decr. fat soluble vitamin absorption; consider 11-17 mg/kg/day PO divided qd-bid if concomitant familial hypertriglyceridemia; give w/ food

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]