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Nubeqa
darolutamide
Adult Dosing .
Dosage forms: TAB: 300 mg
Special Note
- [uses, dosing may vary]
- Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments
prostate CA
- [non-metastatic castration-resistant dz]
- Dose: 600 mg PO bid; Info: use w/ GnRH analog in pts w/o bilateral orchiectomy; give w/ food; do not cut/crush/chew tab
- [metastatic hormone-sensitive dz]
- Dose: 600 mg PO bid; Info: use w/ docetaxel; use w/ GnRH analog in pts w/o bilateral orchiectomy; give w/ food; do not cut/crush/chew tab
renal dosing
- [adjust dose amount]
- eGFR 15-29: 300 mg bid; eGFR <15: not defined
- HD/PD: not defined
hepatic dosing
- [adjust dose amount]
- Child-Pugh Class B: 300 mg bid; Child-Pugh Class C: not defined
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.