Breztri Aerosphere

Adult Dosing .

Dosage forms:  MDI: 160 mcg/9 mcg/4.8 mcg per actuation; 160 mcg/18 mcg/4.8 mcg per actuation

COPD, maintenance tx

[2 puffs (160 mcg/9 mcg/4.8 mcg per actuation) inhaled bid]

Max: 640 mcg/36 mcg/19.2 mcg/day; Info: search 'gold' for epocrates COPD GOLD decision tools

asthma, maintenance tx

[2 puffs (160 mcg/18 mcg/4.8 mcg per actuation) inhaled bid]

Max: 640 mcg/72 mcg/19.2 mcg/day; Info: search 'asthma' for epocrates Asthma Long-Term Management NIH/NHLBI decision tools

renal dosing

[see below]

renal impairment: not defined; Info: caution advised if CrCl <30

HD/PD: not defined, caution advised

hepatic dosing

[see below]

mild-moderate impairment: not defined; severe impairment: not defined, caution advised

Peds Dosing .

Dosage forms:  MDI: 160 mcg/18 mcg/4.8 mcg per actuation

asthma, maintenance tx

[12 yo and older]

Dose: 2 puffs (160 mcg/18 mcg/4.8 mcg per actuation) inhaled bid; Max: 640 mcg/72 mcg/19.2 mcg/day; Info: search 'asthma' for epocrates Asthma Long-Term Management NIH/NHLBI decision tools

renal dosing

[see below]

renal impairment: not defined; Info: caution advised if CrCl <30

HD/PD: not defined, caution advised

hepatic dosing

[see below]

mild-moderate impairment: not defined; severe impairment: not defined, caution advised