Evrysdi

Adult Dosing .

Dosage forms:  TAB: 5 mg; SOLUTION: 0.75 mg per mL

spinal muscular atrophy

[5 mg PO/NG/GT qd]

Info: do not cut/crush/chew tab, but may disperse tab in filtered water

renal dosing

[see below]

renal impairment: no adjustment

HD/PD: not defined

hepatic dosing

[see below]

Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined

Peds Dosing .

Dosage forms:  TAB: 5 mg; SOLUTION: 0.75 mg per mL

spinal muscular atrophy

[oral solution form, <2 mo]

Dose: 0.15 mg/kg/dose PO/NG/GT qd

[oral solution form, 2-23 mo]

Dose: 0.2 mg/kg/dose PO/NG/GT qd

[oral solution form, 2 yo and older, <20 kg]

Dose: 0.25 mg/kg/dose PO/NG/GT qd

[tablet or oral solution form, 2 yo and older, >20 kg]

Dose: 5 mg PO/NG/GT qd; Info: do not cut/crush/chew tab, but may disperse tab in filtered water

renal dosing

[see below]

renal impairment: no adjustment

HD/PD: not defined

hepatic dosing

[see below]

Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined