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Gimoti
metoclopramide nasal
Black Box Warnings .
Tardive Dyskinesia
contraindicated in patients with tardive dyskinesia history; metoclopramide can cause tardive dyskinesia, a serious, potentially irreversible movement disorder; risk incr. with tx duration and total cumulative dosage; use shortest effective tx duration and periodically reassess need for tx; D/C immediately if patient develops tardive dyskinesia signs/symptoms; avoid >12wk tx (if longer-term use unavoidable, then routinely monitor for tardive dyskinesia signs/symptoms)
Adult Dosing .
Dosage forms: SPRAY: 15 mg per actuation
gastroparesis
- [<65 yo]
- Dose: 1 actuation in one nostril qid; Max: 4 actuations/day; 12wk; Info: give 30min before meals and at bedtime
- [65 yo and older]
- Dose: 1 actuation in one nostril qid; Max: 4 actuations/day; 12wk; Info: not for initial tx; for patients stable on metoclopramide 40 mg/day PO/IM/IV; give 30min before meals and at bedtime
renal dosing
- [see below]
- CrCl <60: avoid use
- HD/PD: avoid use
hepatic dosing
- [see below]
- Child-Pugh Class B or C: avoid use
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.