epocrates logo
epocrates logo
epocrates logo
  • 0

Herbs & Supplements

epocrates logo

Sign in to access our clinical decision support tools

Sign in Create Account

Formulary
No Formulary Selected

close

 

Select a medication above to begin.

millepertuis perforé

St. John's wort (Hypericum perforatum)

Sections:

  • Entire Monograph
  • Reported Uses
  • Reported Doses
  • Cautions
  • Drug Interactions
  • Adverse Reactions
  • Synonyms
  • Other Info
  • Add to Interaction Check

Reported Uses

  • NOTE: see Herb & Supplement Effectiveness Rating Definitions table
  • acne [Insufficient Evidence]
  • ADHD [Insufficient Evidence]
  • anxiety [Insufficient Evidence]
  • brain tumor [Insufficient Evidence]
  • burning mouth syndrome [Possibly Ineffective]
  • chronic fatigue syndrome [Insufficient Evidence]
  • Crigler-Najjar syndrome type 2 [Insufficient Evidence]
  • depression [Likely Effective]
  • fibromyalgia [Insufficient Evidence]
  • genital herpes [Insufficient Evidence]
  • hepatitis C [Possibly Ineffective]
  • herpes labialis (cold sores) [Insufficient Evidence]
  • HIV/AIDS [Possibly Ineffective]
  • IBS [Possibly Ineffective]
  • mastitis [Insufficient Evidence]
  • memory [Insufficient Evidence]
  • menopausal symptoms [Possibly Effective]
  • migraine prophylaxis [Insufficient Evidence]
  • obsessive-compulsive disorder [Insufficient Evidence]
  • osteoarthritis [Insufficient Evidence]
  • peripheral neuropathy [Possibly Ineffective]
  • plaque psoriasis [Insufficient Evidence]
  • polycystic ovary syndrome [Insufficient Evidence]
  • premenstrual syndrome [Insufficient Evidence]
  • scleroderma [Insufficient Evidence]
  • seasonal affective disorder [Insufficient Evidence]
  • smoking cessation [Insufficient Evidence]
  • social anxiety disorder [Possibly Ineffective]
  • somatoform disorders [Possibly Effective]
  • tinnitus [Insufficient Evidence]
  • wound healing [Insufficient Evidence]

Copyright © 2026. All Rights Reserved. Republication or redistribution, including by framing or similar means, is prohibited without the prior written consent of copyright holder.

Select a medication above to begin.

Help
FDA Reporting Form
 
Download Epocrates from the App Store Download Epocrates from the Play Store
About Us Features Business Solutions Help & Feedback
© 2026 epocrates, Inc.    Terms of Use Privacy Policy Editorial Policy Do Not Sell or Share My Information