sulfate de berbérine

Reported Uses

• NOTE: see Herb & Supplement Effectiveness Rating Definitions table
• aphthous ulcer (canker sores) [Possibly Effective]
• atrial fibrillation [Insufficient Evidence]
• biliary disorder [Insufficient Evidence]
• burns [Insufficient Evidence]
• cardiovascular dz [Insufficient Evidence]
• CHF [Insufficient Evidence]
• cholera [Insufficient Evidence]
• colorectal adenoma [Insufficient Evidence]
• coronary heart dz [Insufficient Evidence]
• diabetes mellitus, type 2 [Possibly Effective]
• diarrhea [Insufficient Evidence]
• diarrhea, radiation-related [Insufficient Evidence]
• glaucoma [Insufficient Evidence]
• hepatitis B [Insufficient Evidence]
• hepatitis C [Insufficient Evidence]
• H. pylori infection [Possibly Effective]
• HTN [Possibly Effective]
• hyperlipidemia [Possibly Effective]
• IBS [Insufficient Evidence]
• impaired glucose tolerance [Insufficient Evidence]
• menopausal sx [Insufficient Evidence]
• metabolic effects, antipsychotic-induced [Insufficient Evidence]
• metabolic syndrome [Insufficient Evidence]
• nonalcoholic fatty liver dz [Insufficient Evidence]
• obesity [Insufficient Evidence]
• polycystic ovary syndrome [Possibly Effective]
• radiation fibrosis [Insufficient Evidence]
• stroke [Insufficient Evidence]
• thrombocytopenia [Insufficient Evidence]
• trachoma [Insufficient Evidence]
• ulcerative colitis [Insufficient Evidence]
• ventricular arrhythmias [Insufficient Evidence]

Reported Doses

Safety/efficacy may not be established; reported doses may be derived from limited or potentially inadequate studies w/ variable regimens, multi-ingredient products, or where concentration of active ingredients may vary widely

Effectiveness Ratings

[see Herb & Supplement Effectiveness Rating Definitions table]

aphthous ulcer (canker sores)

[Possibly Effective]

Dose: apply 0.5% gel topically qid

atrial fibrillation

[Insufficient Evidence]

Dose: 400 mg PO tid

biliary disorder

[Insufficient Evidence]

Dose: 500-1000 mg PO bid

burns

[Insufficient Evidence]

Dose: apply ointment topically q4h

CHF

[Insufficient Evidence]

Dose: 1.2-2 g PO qd; Info: used w/ conventional tx

cholera

[Insufficient Evidence]

Dose: 400 mg PO x1

colorectal adenoma

[Insufficient Evidence]

Dose: 300 mg PO bid; Alt: 100 mg PO tid

coronary heart dz

[Insufficient Evidence]

Dose: 500 mg PO qd

diabetes mellitus, type 2

[Possibly Effective]

Dose: 500 mg PO bid-tid; Alt: 0.9-3 g/day PO divided bid-tid; 600 mg PO bid; Info: used w/ or w/o conventional tx

diarrhea

[Insufficient Evidence]

Dose: 400 mg PO x1

diarrhea, radiation-related

[Insufficient Evidence]

Dose: 300 mg PO tid

hepatitis B

[Insufficient Evidence]

Dose: 1 g PO qd

hepatitis C

[Insufficient Evidence]

Dose: 1 g PO qd

H. pylori infection

[Possibly Effective]

Dose: 300-500 mg PO bid-tid; Info: used w/ standard tx

HTN

[Possibly Effective]

Dose: 900 mg PO qd; Info: used w/ amlodipine

hyperlipidemia

[Possibly Effective]

Dose: 500-1000 mg PO qd-bid; Alt: 200-500 mg PO tid

IBS

[Insufficient Evidence]

Dose: 400 mg PO bid

impaired glucose tolerance

[Insufficient Evidence]

Dose: 500 mg extract PO tid; Alt: 550 mg PO bid

metabolic effects, antipsychotic-induced

[Insufficient Evidence]

Dose: 300 mg PO bid

metabolic syndrome

[Insufficient Evidence]

Dose: 500 mg PO tid; Alt: 500 mg PO qd

nonalcoholic fatty liver dz

[Insufficient Evidence]

Dose: 500-1000 mg PO bid; Alt: 200-500 mg PO tid; Info: used w/ or w/o metformin

obesity

[Insufficient Evidence]

Dose: 300-1500 mg PO qd

polycystic ovary syndrome

[Possibly Effective]

Dose: 500-550 mg PO bid-tid

radiation fibrosis

[Insufficient Evidence]

Dose: 20 mg/kg/dose PO qd; Start: 1st day of XRT

stroke

[Insufficient Evidence]

Dose: 300-1000 mg PO qd; Info: used w/ conventional tx

thrombocytopenia

[Insufficient Evidence]

Dose: 5 mg PO tid

trachoma, adult pts

[Insufficient Evidence]

Dose: 1 gtt in eye(s) tid; Info: 0.2% or 0.5% solution

trachoma, peds pts

[Insufficient Evidence]

Dose: 1 gtt 0.2% in eye(s) tid

ventricular arrhythmias

[Insufficient Evidence]

Dose: 300-600 mg PO tid-qid; Info: used w/ or w/o antiarrhythmic tx