epocrates logo
epocrates logo
epocrates logo
  • 0

Herbs & Supplements

epocrates logo

Sign in to access our clinical decision support tools

Sign in Create Account

Formulary
No Formulary Selected

close

 

Select a medication above to begin.

lion's mane mushroom (Hericium erinaceus)

common name

Sections:

  • Entire Monograph
  • Reported Uses
  • Reported Doses
  • Cautions
  • Drug Interactions
  • Adverse Reactions
  • Synonyms
  • Other Info
  • Add to Interaction Check

Reported Doses

Safety/efficacy may not be established; reported doses may be derived from limited or potentially inadequate studies with variable regimens, multi-ingredient products, or where concentration of active ingredients may vary widely

Special Note

[formulation clarification]
Info: may include fruiting body and/or mycelial fibers; may contain hericenones, erinacines, other constituents

Effectiveness Ratings

[see Herb & Supplement Effectiveness Rating Definitions table]

Alzheimer disease

[Insufficient Evidence]
Dose: 1.05 g mycelial fibers PO qd; Info: standardized to contain 5 mg/g erinacrine A

cognitive function

[Insufficient Evidence]
Dose: 3.2 g fruiting body powder PO qd; Alt: 1.8 g fruiting body and mycelial fibers PO qam after meal; 1.8 g fruiting body and mycelial fibers PO x1 after meal

cognitive impairment

[Insufficient Evidence]
Dose: 1 g (96% dry powder) PO tid; Info: for patients with mild cognitive impairment

Copyright © 2026. All Rights Reserved. Republication or redistribution, including by framing or similar means, is prohibited without the prior written consent of copyright holder.

Select a medication above to begin.

Help
FDA Reporting Form
 
Download Epocrates from the App Store Download Epocrates from the Play Store
About Us Features Business Solutions Help & Feedback
© 2026 epocrates, Inc.    Terms of Use Privacy Policy Editorial Policy Do Not Sell or Share My Information