epocrates logo
epocrates logo
epocrates logo
  • 0

Herbs & Supplements

epocrates logo

Sign in to access our clinical decision support tools

Sign in Create Account

Formulary
No Formulary Selected

close

 

Select a medication above to begin.

asgandha

ashwagandha (Withania somnifera)

Sections:

  • Entire Monograph
  • Reported Uses
  • Reported Doses
  • Cautions
  • Drug Interactions
  • Adverse Reactions
  • Synonyms
  • Other Info
  • Add to Interaction Check

Entire Monograph

Reported Uses

  • NOTE: see Herb & Supplement Effectiveness Rating Definitions table
  • ADHD [Insufficient Evidence]
  • aging [Insufficient Evidence]
  • androgenic alopecia [Insufficient Evidence]
  • anxiety [Possibly Effective]
  • asthma [Insufficient Evidence]
  • athletic performance [Insufficient Evidence]
  • back pain [Insufficient Evidence]
  • bipolar disorder [Insufficient Evidence]
  • bronchitis [Insufficient Evidence]
  • cerebellar ataxia [Insufficient Evidence]
  • cognitive function [Insufficient Evidence]
  • cognitive impairment [Insufficient Evidence]
  • constipation [Insufficient Evidence]
  • COPD [Insufficient Evidence]
  • COVID-19 [Insufficient Evidence]
  • depression [Insufficient Evidence]
  • diabetes mellitus, type 2 [Insufficient Evidence]
  • fatigue [Insufficient Evidence]
  • fatigue, chemo-related [Insufficient Evidence]
  • fibromyalgia [Insufficient Evidence]
  • generalized anxiety disorder [Possibly Effective]
  • hiccups [Insufficient Evidence]
  • hypercholesterolemia [Insufficient Evidence]
  • hypothyroidism [Insufficient Evidence]
  • infertility in patients of childbearing potential [Insufficient Evidence]
  • insomnia [Possibly Effective]
  • lichen planus [Insufficient Evidence]
  • male infertility [Insufficient Evidence]
  • menopausal symptoms [Insufficient Evidence]
  • metabolic effects, antipsychotic-induced [Insufficient Evidence]
  • obsessive-compulsive disorder [Insufficient Evidence]
  • osteoarthritis [Insufficient Evidence]
  • Parkinson disease [Insufficient Evidence]
  • psychological well-being [Insufficient Evidence]
  • rheumatoid arthritis [Insufficient Evidence]
  • sexual dysfunction [Insufficient Evidence]
  • smoking cessation [Insufficient Evidence]
  • stress [Possibly Effective]
  • tuberculosis [Insufficient Evidence]
  • vitiligo [Insufficient Evidence]
  • wound healing [Insufficient Evidence]
  • wrinkled skin [Insufficient Evidence]

Reported Doses

Safety/efficacy may not be established; reported doses may be derived from limited or potentially inadequate studies with variable regimens, multi-ingredient products, or where concentration of active ingredients may vary widely

Effectiveness Ratings

[see Herb & Supplement Effectiveness Rating Definitions table]

aging

[Insufficient Evidence]
Dose: 600 mg PO qd

androgenic alopecia

[Insufficient Evidence]
Dose: apply 1-2 drops serum topically qd; Info: product containing 5% root extract

anxiety

[Possibly Effective]
Dose: 0.3 g PO bid; Alt: 0.5-12 g PO qd

athletic performance

[Insufficient Evidence]
Dose: 500-1000 mg PO qd; Alt: 120-1250 mg/day PO divided qd-bid

bipolar disorder

[Insufficient Evidence]
Dose: 250 mg PO bid; Start: 250 mg PO qd x1wk

cerebellar ataxia

[Insufficient Evidence]
Dose: 500 mg PO tid

cognitive impairment

[Insufficient Evidence]
Dose: 250 mg PO qd

constipation

[Insufficient Evidence]
Dose: 300-500 mg PO qd; Info: product containing 45% extract in 1:1 ratio ashwagandha root:ambrette fruit

COPD

[Insufficient Evidence]
Dose: 250 mg PO bid; Info: used with conventional tx

COVID-19

[Insufficient Evidence]
Dose: 500-600 mg PO bid

depression

[Insufficient Evidence]
Dose: 500 mg PO qd

diabetes mellitus, type 2

[Insufficient Evidence]
Dose: 3 g PO qd

fatigue

[Insufficient Evidence]
Dose: 200 mg PO bid

fatigue, chemo-related

[Insufficient Evidence]
Dose: 2 g PO tid

generalized anxiety disorder

[Possibly Effective]
Dose: 0.06-1 g PO qd; Alt: 4 g PO tid; Info: used with or without standard tx

hypercholesterolemia

[Insufficient Evidence]
Dose: 3 g PO qd

hypothyroidism

[Insufficient Evidence]
Dose: 300 mg PO bid

insomnia

[Possibly Effective]
Dose: 120-600 mg PO qd

lichen planus

[Insufficient Evidence]
Dose: apply topically bid; Info: for patients with oral lichen planus with gingival presentation

male infertility

[Insufficient Evidence]
Dose: 5 g PO qd; Alt: 225 mg PO tid

menopausal symptoms

[Insufficient Evidence]
Dose: 300 mg PO bid

metabolic effects, antipsychotic-induced

[Insufficient Evidence]
Dose: 400 mg PO tid

obsessive-compulsive disorder

[Insufficient Evidence]
Dose: 120 mg PO qd; Start: 30 mg PO qd x4 days, then incr. by 30 mg/day q4 days; Info: used with selective-serotonin reuptake inhibitor

osteoarthritis

[Insufficient Evidence]
Dose: 900 mg PO tid

Parkinson disease

[Insufficient Evidence]
Dose: 14.5 g PO bid

psychological well-being

[Insufficient Evidence]
Dose: 350 mg PO bid

rheumatoid arthritis

[Insufficient Evidence]
Dose: 5 g PO bid

sexual dysfunction

[Insufficient Evidence]
Dose: 300 mg PO bid

smoking cessation

[Insufficient Evidence]
Dose: 100 mg PO qd

stress

[Possibly Effective]
Dose: 240-1000 mg PO qd; Alt: 300-500 mg PO bid

wrinkled skin

[Insufficient Evidence]
Dose: apply 8% lotion topically qd

Copyright © 2026. All Rights Reserved. Republication or redistribution, including by framing or similar means, is prohibited without the prior written consent of copyright holder.

Select a medication above to begin.

Help
FDA Reporting Form
 
Download Epocrates from the App Store Download Epocrates from the Play Store
About Us Features Business Solutions Help & Feedback
© 2026 epocrates, Inc.    Terms of Use Privacy Policy Editorial Policy Do Not Sell or Share My Information