maneul

Reported Uses

• NOTE: see Herb & Supplement Effectiveness Rating Definitions table
• allergic rhinitis [Insufficient Evidence]
• alopecia areata [Insufficient Evidence]
• angina, unstable [Insufficient Evidence]
• asthma [Insufficient Evidence]
• atherosclerosis [Possibly Effective]
• athletic performance [Insufficient Evidence]
• bladder CA [Insufficient Evidence]
• BPH [Insufficient Evidence]
• bronchitis [Insufficient Evidence]
• cancer prevention, breast [Insufficient Evidence]
• cancer prevention, colorectal [Insufficient Evidence]
• cancer prevention, esophageal [Insufficient Evidence]
• cancer prevention, gastric [Possibly Ineffective]
• cancer prevention, lung [Insufficient Evidence]
• candidiasis, oropharyngeal [Insufficient Evidence]
• candidiasis, vulvovaginal [Insufficient Evidence]
• cardiovascular dz [Insufficient Evidence]
• chronic fatigue syndrome [Insufficient Evidence]
• common cold [Insufficient Evidence]
• corns [Insufficient Evidence]
• coronary heart dz [Insufficient Evidence]
• COVID-19 [Insufficient Evidence]
• cystic fibrosis [Insufficient Evidence]
• dental hypersensitivity [Insufficient Evidence]
• denture stomatitis [Insufficient Evidence]
• diabetes mellitus [Possibly Effective]
• diabetic retinopathy [Insufficient Evidence]
• diarrhea [Insufficient Evidence]
• dysmenorrhea [Insufficient Evidence]
• endometriosis [Possibly Effective]
• exercise-induced muscle soreness [Insufficient Evidence]
• familial hypercholesterolemia [Insufficient Evidence]
• fatigue [Insufficient Evidence]
• fibrocystic breast dz [Insufficient Evidence]
• gastritis [Insufficient Evidence]
• gout [Insufficient Evidence]
• hepatitis [Insufficient Evidence]
• hepatopulmonary syndrome [Insufficient Evidence]
• H. pylori infection [Possibly Ineffective]
• HTN [Possibly Effective]
• hyperlipidemia [Possibly Effective]
• influenza [Insufficient Evidence]
• lead toxicity [Insufficient Evidence]
• metabolic syndrome [Insufficient Evidence]
• mosquito repellent [Insufficient Evidence]
• multiple myeloma [Insufficient Evidence]
• muscle strength [Insufficient Evidence]
• nonalcoholic fatty liver dz [Possibly Effective]
• obesity [Insufficient Evidence]
• onychomycosis [Insufficient Evidence]
• osteoarthritis [Insufficient Evidence]
• otitis media [Insufficient Evidence]
• periodontitis [Possibly Effective]
• peripheral arterial dz [Insufficient Evidence]
• polycystic ovary syndrome [Insufficient Evidence]
• pre-eclampsia [Insufficient Evidence]
• premenstrual syndrome [Insufficient Evidence]
• prostate CA [Insufficient Evidence]
• rheumatoid arthritis [Insufficient Evidence]
• scleroderma [Insufficient Evidence]
• stress [Insufficient Evidence]
• tick repellent [Insufficient Evidence]
• tinea capitis [Insufficient Evidence]
• tinea corporis [Insufficient Evidence]
• tinea cruris [Insufficient Evidence]
• tinea pedis [Insufficient Evidence]
• trichomoniasis [Insufficient Evidence]
• tuberculosis [Insufficient Evidence]
• UTI [Insufficient Evidence]
• warts [Insufficient Evidence]
• wound healing [Insufficient Evidence]

Reported Doses

Safety/efficacy may not be established; reported doses may be derived from limited or potentially inadequate studies w/ variable regimens, multi-ingredient products, or where concentration of active ingredients may vary widely

Special Note, COVID-19

[no scientific data for COVID-19]

Info: see Herb & Supplement Remedy Use in COVID-19 Resources

Special Note

[formulation clarification]

Info: active constituents may incl. allicin, ajoene, other organosulfur compounds

Effectiveness Ratings

[see Herb & Supplement Effectiveness Rating Definitions table]

alopecia areata

[Insufficient Evidence]

Dose: apply 5% gel topically qid; Info: used w/ topical corticosteroid

angina, unstable

[Insufficient Evidence]

Dose: 60 mg IV qd

atherosclerosis

[Possibly Effective]

Dose: 900 mg/day garlic powder PO divided qd-tid; Alt: 300 mg garlic powder PO x1; 150 mg garlic powder PO bid; 250 mg aged garlic extract PO qd; 1200 mg aged garlic extract PO qd-bid

athletic performance

[Insufficient Evidence]

Dose: 900 mg PO x1 before exercise

BPH

[Insufficient Evidence]

Dose: 1 mg/kg/dose garlic extract PO qd

cancer prevention, colorectal

[Insufficient Evidence]

Dose: 2.4 mL aged garlic extract PO qd

candidiasis, oropharyngeal

[Insufficient Evidence]

Dose: apply paste topically qid

candidiasis, vulvovaginal

[Insufficient Evidence]

Dose: apply cream PV qhs

cardiovascular dz

[Insufficient Evidence]

Dose: 250 mg aged black garlic extract PO qd

common cold prevention

[Insufficient Evidence]

Dose: 180 mg allicin PO qd; Alt: 14 mg garlic powder PO qd

corns

[Insufficient Evidence]

Dose: apply liquid extract topically bid

coronary heart dz

[Insufficient Evidence]

Dose: 800-2000 mg PO qd

COVID-19

[Insufficient Evidence]

Dose: 50 mg garlic oil PO bid x10 days; Info: used w/ standard tx

denture stomatitis

[Insufficient Evidence]

Dose: 40 mg/mL mouthwash swish/spit tid

diabetes mellitus

[Possibly Effective]

Dose: 600-1500 mg/day garlic powder PO divided bid-tid; Alt: 8.2 mg garlic oil PO qd; 1000 mg aged garlic extract PO qd; Info: used w/ or w/o metformin

diabetic retinopathy

[Insufficient Evidence]

Dose: 1 g garlic powder PO qd

endometriosis

[Possibly Effective]

Dose: 400 mg garlic powder PO qd; Info: used w/ standard tx

exercise-induced muscle soreness

[Insufficient Evidence]

Dose: 80 mg allicin PO qd

fibrocystic breast dz

[Insufficient Evidence]

Dose: 150 mg garlic powder PO bid

gastritis

[Insufficient Evidence]

Dose: 150 mg garlic powder PO bid

hepatitis

[Insufficient Evidence]

Dose: 150-300 mg garlic oil PO qd

hepatopulmonary syndrome

[Insufficient Evidence]

Dose: 1-2 g/m^2/day garlic oil PO divided bid

HTN

[Possibly Effective]

Dose: 300-1500 mg/day garlic powder PO divided qd-tid; Alt: 2400 mg garlic powder PO x1; 500 mg garlic oil PO qd; 960-7200 mg/day aged garlic extract PO divided qd-tid

hyperlipidemia

[Possibly Effective]

Dose: 600-7200 mg/day aged garlic extract or garlic powder PO divided bid-tid; Alt: 300 mg garlic powder PO bid; 1200 mg PO qd; 250 mg aged garlic extract PO qd; 500 mg garlic oil PO qd

influenza

[Insufficient Evidence]

Dose: 14 mg garlic powder PO qd

lead toxicity

[Insufficient Evidence]

Dose: 400 mg garlic powder PO tid

metabolic syndrome

[Insufficient Evidence]

Dose: 5000-20,000 mg raw garlic PO qd; Alt: 240-6000 mg aged garlic extract PO qd; 188-6000 mg garlic powder PO qd; 2.34 mg ajoene PO qd

nonalcoholic fatty liver dz

[Possibly Effective]

Dose: 800-1600 mg garlic powder PO qd; Alt: 400-800 mg garlic powder PO bid

obesity

[Insufficient Evidence]

Dose: 1600 mg garlic powder PO qd

osteoarthritis

[Insufficient Evidence]

Dose: 500 mg PO bid

periodontitis

[Possibly Effective]

Dose: 1200 mg aged garlic extract PO bid

peripheral arterial dz

[Insufficient Evidence]

Dose: 400 mg PO bid

polycystic ovary syndrome

[Insufficient Evidence]

Dose: 800 mg PO qd

premenstrual syndrome

[Insufficient Evidence]

Dose: 400 mg dried garlic powder PO qd

prostate CA

[Insufficient Evidence]

Dose: 1 mg/kg/dose garlic extract PO qd

rheumatoid arthritis

[Insufficient Evidence]

Dose: 500 mg dried garlic PO bid

tick repellent

[Insufficient Evidence]

Dose: 1200 mg PO qd

tinea corporis

[Insufficient Evidence]

Dose: apply 0.6% ajoene gel topically bid

tinea cruris

[Insufficient Evidence]

Dose: apply 0.6% ajoene gel topically bid

tinea pedis

[Insufficient Evidence]

Dose: apply 0.4-1% ajoene gel topically bid

warts

[Insufficient Evidence]

Dose: apply liquid extract topically bid

wound healing

[Insufficient Evidence]

Dose: apply 30% ointment topically bid