Interaction Check

This page cannot be displayed because your browser has been configured to disable JavaScript, also known as "Active Scripting".Please change your settings and refresh the page.

Sign in to access our clinical decision support tools

Sign in Create Account

Selected Drugs Clear All

MultiCheck Results - 4 Interactions

Avoid/Use Alternative
Junel Fe 24 (norethindrone/ ethinyl estradiol) + Nextstellis (drospirenone/ estetrol)
Avoid/Use Alternative ethinyl estradiol (contraceptive) + estetrol (contraceptive) avoid combo: combo may incr. risk of HTN, thromboembolism, endometrial hyperplasia, other adverse effects (additive effects, duplicate therapy) norethindrone (contraceptive) + drospirenone (contraceptive) avoid combo: combo may incr. risk of thromboembolism, other adverse effects (additive effects, duplicate therapy)
Monitor/Modify Tx
Junel Fe 24 (norethindrone/ ethinyl estradiol) + Tryvio (aprocitentan)
Monitor/Modify Tx ethinyl estradiol (contraceptive) + aprocitentan monitor BP: combo may decr. antihypertensive agent efficacy (antagonistic effects)
Nextstellis (drospirenone/ estetrol) + Tryvio (aprocitentan)
Monitor/Modify Tx estetrol (contraceptive) + aprocitentan monitor BP: combo may decr. antihypertensive agent efficacy (antagonistic effects)