Interaction Check

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MultiCheck Results - 2 Interactions

Monitor/Modify Tx
Annovera (segesterone acetate/ ethinyl estradiol vaginal) + Delsym Cough + Sore Throat (acetaminophen/ dextromethorphan)
Monitor/Modify Tx ethinyl estradiol (contraceptive) + acetaminophen monitor thrombosis s/sx: combo may incr. ethinyl estradiol levels, risk of thromboembolism, other adverse effects (mechanism unknown)
Caution Advised
Annovera (segesterone acetate/ ethinyl estradiol vaginal) + ramelteon (generic)
Caution Advised ethinyl estradiol (contraceptive) + ramelteon caution advised: combo may incr. ramelteon levels, risk of adverse effects (hepatic metabolism inhibited)
Additional Considerations
dextromethorphan in Delsym Cough + Sore Throat
add MAO inhibitor to Interaction Check if recent (14 days) use
segesterone (contraceptive) in Annovera
avoid concurrent use of oil/silicone-based vaginal products, may consider water-based vaginal products; combo may incr. ethinyl estradiol and segesterone exposure, risk of adverse effects; may alter vaginal ring performance, decr. long-term efficacy