Selected Drugs Clear All
MultiCheck Results
- 3
Interactions
Avoid/Use Alternative |
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Chinese goldenseal
(goldenseal (Hydrastis canadensis)) + Virtussin DAC
(codeine/ pseudoephedrine/ guaifenesin) |
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Avoid/Use Alternativegoldenseal + codeine use alternative or monitor respiratory rate, consider decr. codeine dose: combo may incr. codeine and active metabolite morphine levels, risk of CNS and respiratory depression, psychomotor impairment, other adverse effects (hepatic metabolism inhibited, may incr. production of active metabolite morphine) |
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Mimvey
(estradiol/ norethindrone acetate) + Osphena
(ospemifene) |
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Avoid/Use Alternativeestradiol (hormone replacement) + ospemifene avoid combo: combo may alter efficacy of both drugs, incr. risk of thromboembolism, endometrial hyperplasia, other adverse effects (additive effects, antagonistic effects) Monitor/Modify Txnorethindrone (hormone replacement) + ospemifene monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects) |
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Additional Considerations |
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goldenseal
in Chinese goldenseal
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goldenseal may contain varying amounts of berberine and other constituents; interaction potential dependent upon daily berberine intake, may incr. risk of bleeding, hypoglycemia, hypotensive effects |
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codeine
in Virtussin DAC
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consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use add MAO inhibitor to Interaction Check if recent (14 days) use |
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pseudoephedrine
in Virtussin DAC
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add MAO inhibitor to Interaction Check if recent (14 days) use |
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