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Interaction Check

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Selected Drugs Clear All

  • remove carvedilol
    generic
  • remove Ditropan XL
    oxybutynin
  • remove Esidrix
    hydrochlorothiazide
  • remove megestrol
    generic
  • remove Ortho Tri-Cyclen
    norgestimate/ ethinyl estradiol

multicheck MultiCheck Results - 5 Interactions

Smiley face Smiley face

Avoid/Use Alternative

Smiley face Smiley face megestrol (generic) + Ortho Tri-Cyclen (norgestimate/ ethinyl estradiol)

Avoid/Use Alternative


megestrol + norgestimate (contraceptive)

avoid combo: combo may incr. risk of thromboembolism, other adverse effects (additive effects, duplicate therapy)

Monitor/Modify Tx


megestrol + ethinyl estradiol (contraceptive)

monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

Monitor/Modify Tx

Smiley face Smiley face carvedilol (generic) + Ortho Tri-Cyclen (norgestimate/ ethinyl estradiol)

Monitor/Modify Tx


carvedilol + ethinyl estradiol (contraceptive)

monitor BP: combo may decr. antihypertensive agent efficacy (antagonistic effects)

Smiley face Smiley face Esidrix (hydrochlorothiazide) + Ortho Tri-Cyclen (norgestimate/ ethinyl estradiol)

Monitor/Modify Tx


hydrochlorothiazide + ethinyl estradiol (contraceptive)

monitor BP: combo may decr. antihypertensive agent efficacy (antagonistic effects)

Caution Advised

Smiley face Smiley face Ditropan XL (oxybutynin) + Esidrix (hydrochlorothiazide)

Caution Advised


oxybutynin + hydrochlorothiazide

caution advised: combo may incr. hydrochlorothiazide levels, risk of adverse effects (absorption increased)

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