Interaction Check

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MultiCheck Results - 10 Interactions

Contraindicated
Calquence (acalabrutinib) + Varivax (varicella vaccine, live (VAR))
Contraindicated acalabrutinib + varicella vaccine, live contraindicated; vaccinate at least 4wk before or 3mo after acalabrutinib tx: combo may result in inadequate vaccine response, incr. risk of disseminated infection (immunosuppressive effects)
Avoid/Use Alternative
Aurovela Fe 1/20 (norethindrone/ ethinyl estradiol) + Blisovi 24 Fe (norethindrone/ ethinyl estradiol)
Avoid/Use Alternative ethinyl estradiol (contraceptive) + ethinyl estradiol (contraceptive) avoid combo: combo may incr. risk of HTN, thromboembolism, endometrial hyperplasia, other adverse effects (additive effects, duplicate therapy) norethindrone (contraceptive) + norethindrone (contraceptive) avoid combo: combo may incr. risk of thromboembolism, other adverse effects (additive effects, duplicate therapy)
Aurovela Fe 1/20 (norethindrone/ ethinyl estradiol) + Lo-Zumandimine (drospirenone/ ethinyl estradiol)
Avoid/Use Alternative ethinyl estradiol (contraceptive) + ethinyl estradiol (contraceptive) avoid combo: combo may incr. risk of HTN, thromboembolism, endometrial hyperplasia, other adverse effects (additive effects, duplicate therapy) norethindrone (contraceptive) + drospirenone (contraceptive) avoid combo: combo may incr. risk of thromboembolism, other adverse effects (additive effects, duplicate therapy)
Blisovi 24 Fe (norethindrone/ ethinyl estradiol) + Lo-Zumandimine (drospirenone/ ethinyl estradiol)
Avoid/Use Alternative ethinyl estradiol (contraceptive) + ethinyl estradiol (contraceptive) avoid combo: combo may incr. risk of HTN, thromboembolism, endometrial hyperplasia, other adverse effects (additive effects, duplicate therapy) norethindrone (contraceptive) + drospirenone (contraceptive) avoid combo: combo may incr. risk of thromboembolism, other adverse effects (additive effects, duplicate therapy)
Monitor/Modify Tx
Aurovela Fe 1/20 (norethindrone/ ethinyl estradiol) + Calquence (acalabrutinib)
Monitor/Modify Tx ethinyl estradiol (contraceptive) + acalabrutinib monitor CBC: combo may incr. acalabrutinib levels, risk of serious infection, myelosuppression, other adverse effects (hepatic metabolism inhibited)
Blisovi 24 Fe (norethindrone/ ethinyl estradiol) + Calquence (acalabrutinib)
Monitor/Modify Tx ethinyl estradiol (contraceptive) + acalabrutinib monitor CBC: combo may incr. acalabrutinib levels, risk of serious infection, myelosuppression, other adverse effects (hepatic metabolism inhibited)
Calquence (acalabrutinib) + Lo-Zumandimine (drospirenone/ ethinyl estradiol)
Monitor/Modify Tx acalabrutinib + ethinyl estradiol (contraceptive) monitor CBC: combo may incr. acalabrutinib levels, risk of serious infection, myelosuppression, other adverse effects (hepatic metabolism inhibited)