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Interaction Check

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Selected Drugs Clear All

  • remove desvenlafaxine
    generic
  • remove Flomax
    tamsulosin
  • remove glucosamine sulfate-potassium chloride
    glucosamine
  • remove Junel Fe 1.5/ 30
    norethindrone/ ethinyl estradiol
  • remove mannitol
    generic
  • remove NovoLog Mix 70/ 30
    insulin aspart protamine/ insulin aspart
  • remove Xywav
    calcium oxybate/ magnesium oxybate/ potassium oxybate/ sodium oxybate

multicheck MultiCheck Results - 6 Interactions

Smiley face Smiley face

Avoid/Use Alternative

Smiley face Smiley face desvenlafaxine (generic) + Xywav (calcium oxybate/ magnesium oxybate/ potassium oxybate/ sodium oxybate)

Avoid/Use Alternative


desvenlafaxine + oxybate

use alternative or monitor respiratory rate; decr. dose of one or both drugs: combo may incr. risk of profound CNS and respiratory depression, psychomotor impairment, hypotension, syncope (additive effects)

Monitor/Modify Tx

Smiley face Smiley face desvenlafaxine (generic) + Junel Fe 1.5/30 (norethindrone/ ethinyl estradiol)

Monitor/Modify Tx


desvenlafaxine + ethinyl estradiol (contraceptive)

monitor BP: combo may incr. risk of HTN (additive effects)

Smiley face Smiley face desvenlafaxine (generic) + mannitol (generic)

Monitor/Modify Tx


desvenlafaxine + mannitol

monitor sodium: combo may incr. risk of hyponatremia (including life-threatening), seizures (additive effects)

Smiley face Smiley face Junel Fe 1.5/30 (norethindrone/ ethinyl estradiol) + NovoLog Mix 70/30 (insulin aspart protamine/ insulin aspart)

Monitor/Modify Tx


ethinyl estradiol (contraceptive) + insulin

monitor glucose: combo may decr. antidiabetic agent efficacy (antagonistic effects)

norethindrone (contraceptive) + insulin

monitor glucose: combo may decr. antidiabetic agent efficacy (antagonistic effects)

Smiley face Smiley face mannitol (generic) + NovoLog Mix 70/30 (insulin aspart protamine/ insulin aspart)

Monitor/Modify Tx


mannitol + insulin

monitor potassium, ECG: combo may incr. risk of hypokalemia, QT prolongation, cardiac arrhythmias (additive effects)

Additional Considerations

Smiley face Smiley face desvenlafaxine

add MAO inhibitor to Interaction Check if recent (14 days) use

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