Selected Drugs Clear All

  • remove Adderall
    dextroamphetamine/ amphetamine
  • remove morphine sulfate
    generic

multicheck MultiCheck Results - 2 Interactions

Smiley face Smiley face

Avoid/Use Alternative

Smiley face Smiley face Adderall (dextroamphetamine/ amphetamine) + morphine sulfate (generic)

Avoid/Use Alternative


amphetamine + morphine

use alternative or monitor serotonin syndrome sx, especially during initiation/titration; decr. amphetamine start dose: combo may incr. risk of serotonin syndrome (additive effects)

dextroamphetamine + morphine

use alternative or monitor serotonin syndrome sx, especially during initiation/titration; decr. dextroamphetamine start dose: combo may incr. risk of serotonin syndrome (additive effects)

Additional Considerations

Smiley face Smiley face amphetamine in Adderall

add MAO inhibitor to Interaction Check if recent (14 days) use

avoid combo with beverages or products containing ethanol and Adzenys XR-ODT, Dyanavel XR, Mydayis, generic extended-release orally disintegrating tablet (ER ODT) formulations; combo may incr. amphetamine release rate, levels, risk of adverse effects, decr. duration of efficacy

Smiley face Smiley face dextroamphetamine in Adderall

add MAO inhibitor to Interaction Check if recent (14 days) use

avoid combo with beverages or products containing ethanol and Mydayis; combo may incr. dextroamphetamine release rate, levels, risk of adverse effects, decr. duration of efficacy

Smiley face Smiley face morphine in morphine sulfate

consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use

add MAO inhibitor to Interaction Check if recent (14 days) use

avoid combo with beverages or products containing ethanol and some morphine extended-release (ER) capsules; combo may incr. morphine release rate, levels, risk of adverse effects, including life-threatening overdose, decr. duration of efficacy

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