Interaction Check

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MultiCheck Results - 4 Interactions

Avoid/Use Alternative
Liqrev (sildenafil) + Tadliq (tadalafil)
Avoid/Use Alternative sildenafil + tadalafil avoid combo: combo may incr. risk of hypotension, auditory, vestibular, other adverse effects (additive effects, duplicate therapy)
Monitor/Modify Tx
Cobenfy (xanomeline/ trospium) + Tadliq (tadalafil)
Monitor/Modify Tx xanomeline + tadalafil monitor BP: combo may incr. tadalafil levels, risk of hypotension, priapism, other adverse effects (GI metabolism possibly inhibited)
Liqrev (sildenafil) + Tyvaso DPI (treprostinil inhaled)
Monitor/Modify Tx sildenafil + treprostinil monitor BP: combo may incr. risk of severe hypotension, including syncope (additive effects)
Tadliq (tadalafil) + Tyvaso DPI (treprostinil inhaled)
Monitor/Modify Tx tadalafil + treprostinil monitor BP: combo may incr. risk of severe hypotension, including syncope (additive effects)
Additional Considerations
trospium in Cobenfy
avoid combo with beverages or products containing ethanol within 2h of trospium extended-release (ER) capsules administration; combo may incr. trospium release rate, levels, risk of adverse effects, decr. duration of efficacy