Selected Drugs Clear All
MultiCheck Results
- 1
Interaction
Monitor/Modify Tx |
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Arexvy
(respiratory syncytial virus vaccine, adjuvanted (RSV)) + Vyvgart Hytrulo (efgartigimod alfa/hyaluronidase-qvfc)
(efgartigimod alfa/ hyaluronidase) |
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Monitor/Modify Txrespiratory syncytial virus vaccine + efgartigimod alfa if possible, vaccinate at least 2wk before starting efgartigimod alfa tx; otherwise, consider post-immunization titer check or revaccination after immunocompetence restored: combo may result in inadequate vaccine response (immunosuppressive effects) |
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Additional Considerations |
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efgartigimod alfa
in Vyvgart Hytrulo (efgartigimod alfa/hyaluronidase-qvfc)
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consider alternative to efgartigimod alfa with long-term use of drugs that bind to human neonatal Fc receptor (FcRn) (e.g., immunoglobulin products, monoclonal antibodies, or antibody derivates containing the human Fc domain of the IgG subclass); FcRn blockade may decr. systemic exposure, efficacy of such medications |
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